Testosterone Replacement Therapy (TRT)

Testosterone replacement therapy (TRT) is a clinically supervised treatment for men with diagnosed low testosterone — a condition known as hypogonadism. If you have been experiencing persistent fatigue, reduced libido, mood disturbances, difficulty concentrating, loss of muscle mass, or unexplained weight gain, low testosterone could be the underlying cause.

Research shows that testosterone levels in men have been declining decade-on-decade, meaning today's average man may have measurably lower testosterone than his counterpart 50 years ago. At the same time, awareness of TRT has grown substantially, with studies showing that approximately 40% of men under 40 have expressed interest in testosterone optimisation.

How TRT works at Men's Health GP

Our approach is clinically rigorous. TRT is not a lifestyle supplement — it is a medical treatment that requires proper diagnosis, ongoing monitoring, and GP supervision.

• Initial blood work: At least two fasting morning blood tests confirming low total testosterone, plus free testosterone, SHBG, LH, FSH, prolactin, oestradiol, liver function, kidney function, lipid profile, PSA, and full blood count (haematocrit).
• Clinical assessment: Thorough video consultation reviewing symptoms, medical history, current medications, and contraindications.
• Treatment plan: Personalised TRT protocol — testosterone undecanoate injections, gels (1%), or creams.
• Ongoing monitoring: Regular blood tests (every 8–12 weeks initially, then every 6 months) to monitor levels, haematocrit, PSA, and liver function.

What to expect from TRT

Most men notice improvements in energy and mood within 2–4 weeks. Libido typically improves within the first month. Muscle mass and strength improvements take 3–6 months. Full benefits by 6–12 months.

TRT and fertility

Traditional TRT can suppress sperm production. For younger men or those planning families, alternatives such as enclomiphene — which restores natural testosterone production without compromising fertility — may be appropriate. Your GP will discuss all options.

Is TRT legal in Australia?

Yes. TRT is legal with a valid prescription. Testosterone is a Schedule 4 medicine regulated by the TGA. It is illegal to possess or supply without a prescription. All our prescriptions comply with Australian regulations and RACGP guidelines.